Actions and interactions of the IGF system in Alzheimer's disease: review and hypotheses

被引：26

作者：

Lackey, BR ^{[1
]}

Gray, SL ^{[1
]}

Henricks, DM ^{[1
]}

机构：

[1] Clemson Univ, Dept Anim & Vet Sci, Endocrine Physiol Lab, Clemson, SC 29634 USA

来源：

GROWTH HORMONE & IGF RESEARCH | 2000年 / 10卷 / 01期

关键词：

IGF; Alzheimer's; cytokine; apoptosis; diabetes;

D O I：

10.1054/ghir.1999.0129

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Insulin-like growth factors (IGF) are pleiotrophic polypeptides affecting all aspects of growth and development. The IGF system, including ligands, receptors, binding proteins and proteases is also involved in pathophysiological conditions, such as cancer and degenerative conditions. In this review, the actions and interactions of the IGF system as it relates to Alzheimer's disease will be investigated. (C) 2000 Harcourt Publishers Ltd.

引用

页码：1 / 13

页数：13

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