TcruziDB:: an integrated, post-genomics community resource for Trypanosoma cruzi

被引：20

作者：

Aguero, Fernan

Zheng, Wenlong

Weatherly, D. Brent

Mendes, Pablo

Kissinger, Jessica C. ^{[1
]}

机构：

[1] Univ San Martin, Inst Invest Biotecnol, RA-1650 Buenos Aires, DF, Argentina

[2] Univ Georgia, Ctr Trop & Emerging Global Dis, Athens, GA 30602 USA

[3] Univ Georgia, Dept Comp Sci, Athens, GA 30602 USA

[4] Univ Georgia, Dept Genet, Athens, GA 30602 USA

来源：

NUCLEIC ACIDS RESEARCH | 2006年 / 34卷

关键词：

D O I：

10.1093/nar/gkj108

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

TcruziDB (http://TcruziDB.org) is an integrated post-genomics database for the parasitic organism, Trypanosoma cruzi, the causative agent of Chagas' disease. TcruziDB was established in 2003 as a flat-file database with tools for mining the unannotated sequence reads and preliminary contig assemblies emerging from the Tri-Tryp genome consortium (TIGR/SBRI/Karolinska). Today, TcruziDB houses the recently published assembled genomic contigs and annotation provided by the genome consortium in a relational database supported by the Genomics Unified Schema (GUS) architecture. The combination of an annotated genome and a relational architecture has facilitated the integration of genomic data with expression data (proteomic and EST) and permitted the construction of automated analysis pipelines. TcruziDB has accepted, and will continue to accept the deposition of genomic and functional genomic datasets contributed by the research community.

引用

页码：D428 / D431

页数：4

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