Stretchable micro-electrode array

被引:50
作者
Maghribi, M [1 ]
Hamilton, J [1 ]
Polla, D [1 ]
Rose, K [1 ]
Wilson, T [1 ]
Krulevitch, P [1 ]
机构
[1] Lawrence Livermore Natl Lab, Ctr Microtechnol, Livermore, CA USA
来源
2ND ANNUAL INTERNATIONAL IEEE-EMBS SPECIAL TOPIC CONFERENCE ON MICROTECHNOLOGIES IN MEDICINE & BIOLOGY, PROCEEDINGS | 2002年
关键词
retinal prosthesis; PDMS metalization; residual stress; stretchable micro-electrode array;
D O I
10.1109/MMB.2002.1002269
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This paper focuses on the design considerations, fabrication processes, and preliminary testing of a retinal prosthesis that has the potential to aid in vision restoration to millions of blind patients. We are developing an implantable, stretchable micro-electrode array using polymer-based microfabrication techniques. The device will serve as the interface between an electronic imaging system and the human eye, directly stimulating retinal neurons via thin film conducting traces and electroplated electrodes. The metal features are embedded within a thin (similar to50 mum) substrate fabricated using poly (dimethylsiloxane) (PDMS), a biocompatible elastomeric material that has high oxygen permeability and low water permeability. The conformable nature of PDMS is critical for ensuring uniform contact with the curved surface of the retina. To fabricate the device, we developed unique processes for metalizing PDMS to produce robust traces capable of maintaining conductivity when stretched (strain = 7%, SD 1), and for selectively passivating the conductive elements. An in situ substrate curvature measurement taken while curing the PDMS revealed a tensile residual strain of 10%, explaining the stretchable nature of the thin metalized devices.
引用
收藏
页码:80 / 83
页数:4
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