The epidemiology of osteoarthritis

被引：1020

作者：

Johnson, Victoria L. ^{[1
]}

Hunter, David J. ^{[2
,3
]}

机构：

[1] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia

[2] Univ Sydney, Royal N Shore Hosp, Dept Rheumatol, Sydney, NSW 2006, Australia

[3] Univ Sydney, Kolling Inst, Sydney, NSW 2006, Australia

来源：

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2014年 / 28卷 / 01期

基金：

澳大利亚研究理事会;

关键词：

Osteoarthritis; Aetiology; Epidemiology; ANTERIOR CRUCIATE LIGAMENT; SYMPTOMATIC KNEE OSTEOARTHRITIS; OBESE OLDER-ADULTS; ARTICULAR-CARTILAGE; HIP OSTEOARTHRITIS; RISK-FACTORS; WEIGHT-LOSS; VITAMIN-D; RADIOGRAPHIC OSTEOARTHRITIS; FRAMINGHAM OSTEOARTHRITIS;

D O I：

10.1016/j.berh.2014.01.004

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Osteoarthritis (OA) is a leading cause of disability and its incidence is rising due to increasing obesity and an ageing population. Risk factors can be divided into person-level factors, such as age, sex, obesity, genetics, race/ethnicity and diet, and joint-level factors including injury, malalignment and abnormal loading of the joints. The interaction of these risk factors is complex and provides a challenge to the managing physician. The purpose of this review is to illustrate how each of these factors interact together to instigate incident OA as well as to outline the need for ongoing epidemiologic studies for the future prevention of both incident and progressive OA. It is only by understanding the impact of this disease and the modifiable risk factors that we will be able to truly target public health prevention interventions appropriately. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：5 / 15

页数：11

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