A facile synthesis of 2-N(methyl amino) benzothiazoles

被引：23

作者：

Ambati, NB ^{[1
]}

Anand, V ^{[1
]}

Hanumanthu, P ^{[1
]}

机构：

[1] OSMANIA UNIV,DEPT CHEM,HYDERABAD 500007,ANDHRA PRADESH,INDIA

来源：

SYNTHETIC COMMUNICATIONS | 1997年 / 27卷 / 09期

关键词：

D O I：

10.1080/00397919708006084

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of aromatic primary amines with methylisothiocyanate (MITC) yielded N-methyl-N-1-(benzelene-1-yl) thioureas which underwent oxidative cyclization in the presence of bromine in acetic acid, at room temperature, affording the title compounds.

引用

页码：1487 / 1493

页数：7

共 6 条

[1]

BARNIKOW G, 1965, Z CHEM, V5, P62

[2] BROMINE-INDUCED CYCLIZATION OF 1-ACYL-3-(3-THIENYL)-2-THIOUREAS TO 2-ACYLAMINOTHIENO[3,2-D]THIAZOLES [J].

GREHN, L .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1978, 15 (01) :81-87

[3] The unsaturation and tautomeric mobility of heterocyclic compounds. Part I. Benzthiazole and dihydrobenzthiazole derivatives. [J].

Hunter, RF .

JOURNAL OF THE CHEMICAL SOCIETY, 1930, :125-147

[4] HETEROCYCLES .133. INDAZOLES IN ORGANIC SYNTHESIS - FORMATION OF SOME FUSED HETEROCYCLES [J].

KOREN, B ;

KOVAC, F ;

PETRIC, A ;

STANOVNIK, B ;

TISLER, M .

TETRAHEDRON, 1976, 32 (04) :493-497

[5] HETEROCYCLIC SUBSTITUTED UREAS .2. IMMUNOSUPPRESSIVE AND ANTIVIRAL ACTIVITY OF BENZOTHIAZOLE- AND BENZOXAZOLEUREAS [J].

PAGET, CJ ;

KISNER, K ;

STONE, RL ;

DELONG, DC .

JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (06) :1016-&

[6]

VERCEK B, 1978, HETEROCYCLES, V11, P313

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