The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450cam:: potential applications in bioremediation

被引：11

作者：

Jones, JP ^{[1
]}

O'Hare, EJ ^{[1
]}

Wong, LL ^{[1
]}

机构：

[1] Univ Oxford, Inorgan Chem Lab, Dept Chem, Oxford OX1 3QR, England

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 03期

关键词：

D O I：

10.1039/a909536e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Polychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus providing a basis for novel systems for biological clean-up of these inert compounds.

引用

页码：247 / 248

页数：2

共 13 条

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