Eukaryotic DNA polymerases, a growing family

被引：170

作者：

Hübscher, U

Nasheuer, HP

Syväoja, JE

机构：

[1] Univ Zurich Irchel, Inst Vet Biochem, CH-8057 Zurich, Switzerland

[2] Inst Mol Biotechnol, Dept Biochem, D-07745 Jena, Germany

[3] Univ Oulu, Dept Biochem, FIN-90570 Oulu, Finland

[4] Univ Oulu, Bioctr, FIN-90570 Oulu, Finland

[5] Univ Joensuu, Dept Biol, FIN-80100 Joensuu, Finland

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2000年 / 25卷 / 03期

基金：

芬兰科学院;

关键词：

D O I：

10.1016/S0968-0004(99)01523-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In eukaryotic cells, DNA polymerases are required to maintain the integrity of the genome during processes, such as DNA replication, various DNA repair events, translesion DNA synthesis, DNA recombination, and also in regulatory events, such as cell cycle control and DNA damage checkpoint function. In the last two years, the number of known DNA polymerases has increased to at least nine (called alpha, beta, gamma, epsilon, zeta, eta, theta, and iota), and yeast Saccharomyces cerevisiae contains REV1 deoxycytidyl transferase.

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收藏

页码：143 / 147

页数：5

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