Easily accessible chiral amino-phosphinite ligands for highly enantioselective palladium-mediated allylic alkylation

被引：30

作者：

Chen, GS

Li, X

Zhang, HL

Gong, LZ ^{[1
]}

Mi, AQ

Cui, X

Jiang, YZ

Choi, MCK

Chan, ASC

机构：

[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Union Lab Asymmetr Synth, Chengdu 610041, Peoples R China

[2] Hong Kong Polytech Univ, Open Lab Chirotechnol, Hong Kong, Hong Kong, Peoples R China

[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 08期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0957-4166(02)00204-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Palladium-catalyzed asymmetric allylic alkylation of 1,3-diplienyl-2-propenyl acetate with the dimethyl malonate-BSA-LiOAc system has been successfully carried out in the presence of easily prepared new chiral amino-phosphinite ligands such as 3b and 3c to result in good yields and excellent enantioselectivities of up to 95%, e.e. (C) 2002 Published by Elsevier Science Ltd.

引用

收藏

页码：809 / 813

页数：5

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