Toll-like receptors and microbes take aim at each other

被引：54

作者：

Underhill, DM ^{[1
]}

机构：

[1] Inst Syst Biol, Seattle, WA 98103 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2004年 / 16卷 / 04期

关键词：

D O I：

10.1016/j.coi.2004.05.012

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Toll-like receptors (TLRs) are key components of effective innate immunity. As such, pathogenic microorganisms must evade recognition by TLRs, manipulate the consequences of TLR activation, or contend with the inflammatory consequences of TLR activation. Recent studies have improved our understanding of the various mechanisms by which pathogenic organisms manipulate the TLR recognition system.

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页码：483 / 487

页数：5

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