From sarcopenia to frailty: a road less traveled

被引：182

作者：

Morley, John E. ^{[1
]}

von Haehling, Stephan ^{[2
]}

Anker, Stefan D. ^{[2
]}

Vellas, Bruno ^{[3
]}

机构：

[1] St Louis Univ, Sch Med, Div Geriatr Med & Endocrinol, St Louis, MO 63104 USA

[2] Charite Univ Med Berlin, Dept Cardiol, Campus Virchow Klinikum, Berlin, Germany

[3] CHU Toulouse, Gerontol Clin, Toulouse, France

来源：

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE | 2014年 / 5卷 / 01期

关键词：

SKELETAL-MUSCLE; OLDER-ADULTS; PHYSICAL FUNCTION; VITAMIN-D; COGNITIVE IMPAIRMENT; BODY-COMPOSITION; PROTEIN-INTAKE; DOUBLE-BLIND; ELDERLY-MEN; TASK-FORCE;

D O I：

10.1007/s13539-014-0132-3

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

030301 [社会学]; 100201 [内科学];

摘要：

The physical frailty phenotype consists of fatigue, weight loss, and loss of muscle power. Sarcopenia has been shown to be a major cause of frailty. Six societies including SCWD published a consensus suggesting that all persons older than 70 years of age should be screened for frailty when seeing health professionals. Simple screening tests such as the FRAIL (fatigue, resistance, aerobic, illness, and loss of weight) scale can be used. It is felt that frailty can be treated by exercise (resistance and aerobic), high quality protein, vitamin D, and treatment of the common causes of fatigue. It is expected that this approach will decrease disability in older persons.

引用

收藏

页码：5 / 8

页数：4

相关论文

共 55 条

[1]

Are there any benefits of exercise training in cancer cachexia? [J].

Argiles, Josep M. ;

Busquets, Silvia ;

Lopez-Soriano, Francisco J. ;

Costelli, Paola ;

Penna, Fabio .

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2012, 3 (02) :73-76

[2]

Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group [J].

Bauer, Juergen ;

Biolo, Gianni ;

Cederholm, Tommy ;

Cesari, Matteo ;

Cruz-Jentoft, Alfonso J. ;

Morley, John E. ;

Phillips, Stuart ;

Sieber, Cornel ;

Stehle, Peter ;

Teta, Daniel ;

Visvanathan, Renuka ;

Volpi, Elena ;

Boirie, Yves .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2013, 14 (08) :542-559

[3]

Fighting Sarcopenia in Older Frail Subjects: Protein Fuel for Strength, Exercise for Mass [J].

Boirie, Yves .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2013, 14 (02) :140-143

[4]

Frailty and cognitive impairment as predictors of mortality in older Mexican Americans [J].

Cano, C. ;

Samper-Ternent, R. ;

Al Snih, S. ;

Markides, K. ;

Ottenbacher, K. J. .

JOURNAL OF NUTRITION HEALTH & AGING, 2012, 16 (02) :142-147

[5]

Research on cachexia, sarcopenia and skeletal muscle in cardiology [J].

Coats, Andrew J. S. .

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2012, 3 (04) :219-223

[6]

Sarcopenia: European consensus on definition and diagnosis [J].

Cruz-Jentoft, Alfonso J. ;

Baeyens, Jean Pierre ;

Bauer, Juergen M. ;

Boirie, Yves ;

Cederholm, Tommy ;

Landi, Francesco ;

Martin, Finbarr C. ;

Michel, Jean-Pierre ;

Rolland, Yves ;

Schneider, Stephane M. ;

Topinkova, Eva ;

Vandewoude, Maurits ;

Zamboni, Mauro .

AGE AND AGEING, 2010, 39 (04) :412-423

[7]

The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial [J].

Dalton, James T. ;

Barnette, Kester G. ;

Bohl, Casey E. ;

Hancock, Michael L. ;

Rodriguez, Domingo ;

Dodson, Shontelle T. ;

Morton, Ronald A. ;

Steiner, Mitchell S. .

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2011, 2 (03) :153-161

[8]

Cachexia: A new definition [J].

Evans, William J. ;

Morley, John E. ;

Argiles, Josep ;

Bales, Connie ;

Baracos, Vickie ;

Guttridge, Denis ;

Jatoi, Aminah ;

Kalantar-Zadeh, Kamyar ;

Lochs, Herbert ;

Mantovani, Giovanni ;

Marks, Daniel ;

Mitch, William E. ;

Muscaritoli, Maurizio ;

Najand, Armine ;

Ponikowski, Piotr ;

Rossi Fanelli, Filippo ;

Schambelan, Morrie ;

Schols, Annemie ;

Schuster, Michael ;

Thomas, David ;

Wolfe, Robert ;

Anker, Stefan D. ;

Boyce, Amanda ;

Nuckolls, Glen .

CLINICAL NUTRITION, 2008, 27 (06) :793-799

[9]

Cachexia as a major public health problem: frequent, costly, and deadly [J].

Farkas, Jerneja ;

von Haehling, Stephan ;

Kalantar-Zadeh, Kamyar ;

Morley, John E. ;

Anker, Stefan D. ;

Lainscak, Mitja .

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2013, 4 (03) :173-178

[10]

Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia [J].

Fielding, Roger A. ;

Vellas, Bruno ;

Evans, William J. ;

Bhasin, Shalender ;

Morley, John E. ;

Newman, Anne B. ;

van Kan, Gabor Abelian ;

Andrieu, Sandrine ;

Bauer, Juergen ;

Breuille, Denis ;

Cederholm, Tommy ;

Chandler, Julie ;

De Meynard, Capucine ;

Donini, Lorenzo ;

Harris, Tamara ;

Kannt, Aimo ;

Guibert, Florence Keime ;

Onder, Graziano ;

Papanicolaou, Dimitris ;

Rolland, Yves ;

Rooks, Daniel ;

Sieber, Cornet ;

Souhami, Elisabeth ;

Verlaan, Sjors ;

Zamboni, Mauro .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2011, 12 (04) :249-256

← 1 2 3 4 5 6 →