Novel titanium foam for bone tissue engineering

被引:186
作者
Wen, CE [1 ]
Yamada, Y [1 ]
Shimojima, K [1 ]
Chino, Y [1 ]
Hosokawa, H [1 ]
Mabuchi, M [1 ]
机构
[1] Natl Inst Adv Ind Sci & Technol, AIST, Inst Struct & Engn Mat, Moriyama Ku, Nagoya, Aichi 4638560, Japan
关键词
D O I
10.1557/JMR.2002.0382
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Titanium foams fabricated by a new powder metallurgical process have bimodal pore distribution architecture (i.e., macropores and micropores), mimicking natural bone. The mechanical properties of the titanium foam with low relative densities of approximately 0.20-0.30 are close to those of human cancellous bone. Also, mechanical properties of the titanium foams with high relative densities of approximately 0.50-0.65 are close to those of human cortical bone. Furthermore, titanium foams exhibit good ability to form a bonelike apatite layer throughout the foams after pretreatment with a simple thermochemical process and then immersion in a simulated body fluid. The present study illustrates the feasibility of using the titanium foams as implant materials in bone tissue engineering applications, highlighting their excellent biomechanical properties and bioactivity.
引用
收藏
页码:2633 / 2639
页数:7
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