Spectroscopic study of bio-functionalized nanodiamonds

被引：167

作者：

Chung, P. -H.

Perevedentseva, E.

Tu, J. -S.

Chang, C. C.

Cheng, C. -L.

机构：

[1] Natl Dong Hwa Univ, Dept Phys, Shoufeng 974, Hualien, Taiwan

[2] Russian Acad Sci, PN Lebedev Phys Inst, Moscow 117901, Russia

[3] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu, Taiwan

来源：

关键词：

nanodiamonds; biomedical applications; sensors; surface characterization;

D O I：

10.1016/j.diamond.2005.11.019

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Nano-scale materials with attached biomolecules on the surface can be used as bioprobes in cell and tissue analysis. The conjugation of these nanoparticles with biomolecules is one of the key steps in the development of bioprobes. In this work nanometer-sized diamonds (5 and 100 nm) are functionalized and conjugated with protein lysozyme via physical adsorption. The process of creating functional groups on the nanodiamond surface is studied using Fourier Transform Infrared-spectroscopy (FTIR). The conjugation of nanodiamonds with biontolecules and nanodiamond-biomolecule interaction are analyzed with UV/VIS and FTIR spectroscopy. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：622 / 625

页数：4

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