Antioxidative and free radical scavenging activities of selected medicinal herbs

被引:413
作者
Liu, F
Ng, TB [1 ]
机构
[1] Chinese Univ Hong Kong, Fac Med, Dept Biochem, Shatin, NT, Peoples R China
[2] Nankai Univ, Dept Microbiol, Tianjin 300071, Peoples R China
关键词
medicinal herbs; antioxidant; free radical; peroxidation;
D O I
10.1016/S0024-3205(99)00643-8
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The antioxidative and superoxide- and hydroxyl radical-scavenging activities and prooxidant effect of twelve selected medicinal herbs were studied. The aqueous extracts of Coptis chinensis, Paeonia suffruticosa, Prunella vulgaris and Senecio scandens exhibited the highest potency in inhibiting rat erythrocyte hemolysis and lipid peroxidation in rat kidney and brain homogenates. The aforementioned four herbs also demonstrated strong superoxide- and hydroxyl radical-scavenging activity, but exerted only a slight pro-oxidant effect.
引用
收藏
页码:725 / 735
页数:11
相关论文
共 20 条
[1]   ANTIOXIDANT ACTIONS OF THYMOL, CARVACROL, 6-GINGEROL, ZINGERONE AND HYDROXYTYROSOL [J].
AESCHBACH, R ;
LOLIGER, J ;
SCOTT, BC ;
MURCIA, A ;
BUTLER, J ;
HALLIWELL, B ;
ARUOMA, OI .
FOOD AND CHEMICAL TOXICOLOGY, 1994, 32 (01) :31-36
[2]   Characterization of the antioxidant effects of melatonin and related indoleamines in vitro [J].
Chan, TY ;
Tang, PL .
JOURNAL OF PINEAL RESEARCH, 1996, 20 (04) :187-191
[3]  
CHANG RS, 1988, ANTIVIR RES, V9, P163, DOI 10.1016/0166-3542(88)90001-0
[4]   Use of the Trolox assay to estimate the antioxidant content of seventeen edible wild plants of Niger [J].
Cook, JA ;
VanderJagt, DJ ;
Dasgupta, A ;
Mounkaila, G ;
Glew, RS ;
Blackwell, W ;
Glew, RH .
LIFE SCIENCES, 1998, 63 (02) :105-110
[5]  
Halliwell B, 1996, ANNU REV NUTR, V16, P33, DOI 10.1146/annurev.nu.16.070196.000341
[6]   THE ANTIOXIDANTS OF HUMAN EXTRACELLULAR FLUIDS [J].
HALLIWELL, B ;
GUTTERIDGE, JMC .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1990, 280 (01) :1-8
[7]   Antioxidative action of diterpenoids from Podocarpus nagi [J].
Haraguchi, H ;
Ishikawa, H ;
Kubo, I .
PLANTA MEDICA, 1997, 63 (03) :213-215
[8]  
HU TX, 1992, ACTA BIOCH BIOPH SIN, V24, P465
[9]   Free radical scavenging activities of mushroom polysaccharide extracts [J].
Liu, F ;
Ooi, VEC ;
Chang, ST .
LIFE SCIENCES, 1997, 60 (10) :763-771
[10]   FREE-RADICAL CHAIN OXIDATION OF RAT RED-BLOOD-CELLS BY MOLECULAR-OXYGEN AND ITS INHIBITION BY ALPHA-TOCOPHEROL [J].
MIKI, M ;
TAMAI, H ;
MINO, M ;
YAMAMOTO, Y ;
NIKI, E .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1987, 258 (02) :373-380