Structural characterization of human Ad4BP (SF-1) gene

被引:59
作者
Oba, K
Yanase, T
Nomura, M
Morohashi, K
Takayanagi, R
Nawata, H
机构
[1] KYUSHU UNIV,FAC MED,DEPT INTERNAL MED 3,HIGASHI KU,FUKUOKA 812,JAPAN
[2] KYUSHU UNIV,FAC MED,GRAD SCH MED SCI,DEPT MOL BIOL,HIGASHI KU,FUKUOKA 812,JAPAN
关键词
D O I
10.1006/bbrc.1996.1343
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ad4BP (or steroidogenic factor 1, SF-1) has been implicated to be an essential transcriptional factor for steroidogenesis as well as for the development of the reproductive axis. We elucidated the structure of the human Ad4BP gene. The gene is about 30 kb long and is split into 7 exons including a non-coding exon 1. The deduced amino acid sequence of the human Ad4BP consists of 461 amino acid residues and was highly homologous to those of other mammalian species. (C) 1996 Academic Press, Inc.
引用
收藏
页码:261 / 267
页数:7
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