Microwave-mediated solventless synthesis of new derivatives of marine alkaloid Leucettamine B

被引：30

作者：

Chérouvrier, JR ^{[1
]}

Carreaux, F ^{[1
]}

Bazureau, JP ^{[1
]}

机构：

[1] Univ Rennes 1, Inst Chim Synth & Electrosynth Organ 3, UMR 6510, F-35042 Rennes, France

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 19期

关键词：

2-amino imidazolone; leucettamine B derivatives; solvent-free; condensation; microwaves guanylation;

D O I：

10.1016/S0040-4039(02)00575-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New access to N-alkyl derivatives of the marine alkaloid Leucettamine B are described using two three-step convergent routes. For the formation of the 2-amino imidazolone ring, the key steps involve solvent-free condensations under microwaves and guanylation reactions with non-sterically hindered primary amines. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：3581 / 3584

页数：4

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