Gram-scale synthesis of (+)-discodermolide

被引：126

作者：

Smith, AB ^{[1
]}

Kaufman, MD

Beauchamp, TJ

LaMarche, MJ

Arimoto, H

机构：

[1] Univ Penn, Monell Chem Senses Ctr, Dept Chem, Philadelphia, PA 19104 USA

[2] Univ Penn, Res Struct Matter Lab, Dept Chem, Philadelphia, PA 19104 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 11期

关键词：

D O I：

10.1021/ol9910870

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] triply convergent, highly efficient second-generation synthesis of the potent antimitotic agent (+)-discodermolide (1) has been achieved on a 1-g scale.

引用

页码：1823 / 1826

页数：4

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