Generation of pancreatic insulin-producing cells from embryonic stem cells - 'Proof of principle', but questions still unanswered

被引：24

作者：

Rolletschek, A. ^{[1
]}

Kania, G. ^{[1
]}

Wobus, A. M. ^{[1
]}

机构：

[1] Leibniz Inst Plant Genet & Crop Plant Res, In Vitro Differentiat Grp, D-06466 Gatersleben, Germany

来源：

DIABETOLOGIA | 2006年 / 49卷 / 11期

关键词：

embryonic stem cells; insulin-producing cells;

D O I：

10.1007/s00125-006-0441-y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：2541 / 2545

页数：5

共 52 条

[41] Differentiation of mouse embryonic stem cells to insulin-producing cells [J].

Schroeder, Insa S. ;

Rolletschek, Alexandra ;

Blyszczuk, Przemyslaw ;

Kania, Gabriela ;

Wobus, Anna M. .

NATURE PROTOCOLS, 2006, 1 (02) :495-507

[42]

Schwitzgebel VM, 2000, DEVELOPMENT, V127, P3533

[43] Embryonic stem cell-based diabetes therapy - a long road to travel [J].

Serup, P. .

DIABETOLOGIA, 2006, 49 (11) :2537-2540

[44] Inducing embryonic stem cells to differentiate into pancreatic β cells by a novel three-step approach with activin A and all-trans retinoic acid [J].

Shi, Y ;

Hou, LL ;

Tang, FC ;

Jiang, W ;

Wang, PG ;

Ding, MX ;

Deng, HK .

STEM CELLS, 2005, 23 (05) :656-662

[45] Insulin expressing cells from differentiated embryonic stem cells are not beta cells [J].

Sipione, S ;

Eshpeter, A ;

Lyon, JG ;

Korbutt, GS ;

Bleackley, RC .

DIABETOLOGIA, 2004, 47 (03) :499-508

[46] Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice [J].

Soria, B ;

Roche, E ;

Berná, G ;

León-Quinto, T ;

Reig, JA ;

Martín, F .

DIABETES, 2000, 49 (02) :157-162

[47] The Pax4 gene is essential for differentiation of insulin-producing beta cells In the mammalian pancreas [J].

SosaPineda, B ;

Chowdhury, K ;

Torres, M ;

Oliver, G ;

Gruss, P .

NATURE, 1997, 386 (6623) :399-402

[48] Similarities of K+ATP channel expression and Ca2+ changes in pancreatic β cells and hypothalamic neurons [J].

Squires, PE ;

Churamani, D ;

Pararajasingam, R ;

Persaud, SJ ;

Jones, PM .

PANCREAS, 2005, 30 (03) :227-232

[49] Pax6 Is required for differentiation of glucagon-producing alpha-cells in mouse pancreas [J].

StOnge, L ;

SosaPineda, B ;

Chowdhury, K ;

Mansouri, A ;

Gruss, P .

NATURE, 1997, 387 (6631) :406-409

[50] Epithelial-mesenchymal transitions in development and pathologies [J].

Thiery, JP .

CURRENT OPINION IN CELL BIOLOGY, 2003, 15 (06) :740-746

← 1 2 3 4 5 6 →