The radical cation of N,N-diethyl-para-paraphenylendiamine:: A possible indicator of oxidative stress in biological samples.

被引:306
作者
Alberti, A [1 ]
Bolognini, L
Macciantelli, D
Caratelli, M
机构
[1] I Co CEA, CNR, Area Ric, I-40129 Bologna, Italy
[2] Diacron Srl, Div Diagnost, I-58100 Grosseto, Italy
关键词
D O I
10.1163/156856700X00769
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The alkoxy and peroxy radicals formed in the degradation of hydroperoxides brought about by transition metal ions in acidic media can convert substrates with suitably low oxidation potentials, such as N,N-diethyl-para-phenylendiamine, to the corresponding radical cations. The possibility that these reactions are used in the evaluation of oxidative stress in human beings is discussed.
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页码:253 / 267
页数:15
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