Sol-gel materials for electrochemical biosensors

被引:300
作者
Wang, J [1 ]
机构
[1] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA
关键词
biosensors; electroanalysis; sol-gel processes; immobilization; enzyme electrodes;
D O I
10.1016/S0003-2670(99)00572-3
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An overview is presented of the state-of-the art of electrochemical biosensors employing sol-gel materials. Low-temperature, porous sol-gel ceramics represent a relatively new class of materials for the immobilization of biomolecules. The rational design of sol-gel sensing materials, based on the judicious choice of the starting alkoxide, encapsulated reagents, and preparation conditions, allows tailoring of material properties in a wide range, and offers great promise for the development of electrochemical biosensors. The various advantages of biogels for amperometric biosensing are discussed, along with common designs of sol-gel-derived bioelectrodes, recent advances and trends, and future prospects. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:21 / 27
页数:7
相关论文
共 42 条
  • [1] [Anonymous], 1996, HDB CHEM BIOL SENSOR
  • [2] ENZYMES AND OTHER PROTEINS ENTRAPPED IN SOL-GEL MATERIALS
    AVNIR, D
    BRAUN, S
    LEV, O
    OTTOLENGHI, M
    [J]. CHEMISTRY OF MATERIALS, 1994, 6 (10) : 1605 - 1614
  • [3] Sol-gel matrixes doped with atrazine antibodies: Atrazine binding properties
    Bronshtein, A
    Aharonson, N
    Avnir, D
    Turniansky, A
    Altstein, M
    [J]. CHEMISTRY OF MATERIALS, 1997, 9 (11) : 2632 - 2639
  • [4] THE SOL-GEL PREPARATION OF SILICA-GELS
    BUCKLEY, AM
    GREENBLATT, M
    [J]. JOURNAL OF CHEMICAL EDUCATION, 1994, 71 (07) : 599 - 602
  • [5] Analytical applications of organically modified silicates
    Collinson, MM
    [J]. MIKROCHIMICA ACTA, 1998, 129 (3-4) : 149 - 165
  • [6] SOL-GEL ENCAPSULATION METHODS FOR BIOSENSORS
    DAVE, BC
    DUNN, B
    VALENTINE, JS
    ZINK, JI
    [J]. ANALYTICAL CHEMISTRY, 1994, 66 (22) : A1120 - A1127
  • [7] Encapsulation of biologicals within silicate, siloxane, and hybrid sol-gel polymers: An efficient and generic approach
    Gill, I
    Ballesteros, A
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (34) : 8587 - 8598
  • [8] SOL-GEL VANADIUM PENTAOXIDE GLUCOSE BIOSENSOR
    GLEZER, V
    LEV, O
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (06) : 2533 - 2534
  • [9] Sol-gel derived, ferrocenyl-modified silicate-graphite composite electrode: Wiring of glucose oxidase
    Gun, J
    Lev, O
    [J]. ANALYTICA CHIMICA ACTA, 1996, 336 (1-3) : 95 - 106
  • [10] Screen-printable surfactant-induced sol-gel graphite composites for electrochemical sensors
    Guo, YZ
    Guadalupe, AR
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 1998, 46 (03) : 213 - 219