Sol-gel materials for electrochemical biosensors

被引:300
作者
Wang, J [1 ]
机构
[1] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA
关键词
biosensors; electroanalysis; sol-gel processes; immobilization; enzyme electrodes;
D O I
10.1016/S0003-2670(99)00572-3
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An overview is presented of the state-of-the art of electrochemical biosensors employing sol-gel materials. Low-temperature, porous sol-gel ceramics represent a relatively new class of materials for the immobilization of biomolecules. The rational design of sol-gel sensing materials, based on the judicious choice of the starting alkoxide, encapsulated reagents, and preparation conditions, allows tailoring of material properties in a wide range, and offers great promise for the development of electrochemical biosensors. The various advantages of biogels for amperometric biosensing are discussed, along with common designs of sol-gel-derived bioelectrodes, recent advances and trends, and future prospects. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:21 / 27
页数:7
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