Metabolic impact of obesity in childhood

被引:57
作者
Caprio, S
Tamborlane, WV
机构
[1] Yale Univ, Sch Med, Dept Pediat, Div Endocrinol, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Yale Gen Clin Res Ctr, New Haven, CT 06520 USA
关键词
D O I
10.1016/S0889-8529(05)70099-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Childhood obesity currently is a growing problem in the United States. Using the euglycemic-hyperinsulinemic and hyperglycemic clamp techniques along with magnetic resonance imaging, the authors examined changes in glucose and lipid metabolism in vivo and their relationship to fat distribution in obese children. The studies indicated that increased visceral fat, hyperinsulinemia, and insulin resistance are closely linked abnormalities that are expressed early in the natural history of obesity.
引用
收藏
页码:731 / +
页数:18
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