The role of soy phytoestrogens in prostate cancer

被引：44

作者：

Castle, EP ^{[1
]}

Thrasher, JB ^{[1
]}

机构：

[1] Univ Kansas, Med Ctr, Dept Surg, Div Urol, Kansas City, KS 66160 USA

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2002年 / 29卷 / 01期

关键词：

D O I：

10.1016/S0094-0143(02)00019-8

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Epidemiological data of phytoestrogens and prostate cancer strongly supports the cancer protective effects of isoflavones found in soy products. Inhibition of cell proliferation via hormone-dependent and hormone-independent mechanisms by soy phytochemicals has been studied extensively in cell culture and animal studies. Herein, we review the current literature on the epidemiology and effects of two soy phytoestrogens, genistein and daidzein, and would stress the need for controlled human trials to assess the true preventive and therapeutic effects of these compounds.

引用

页码：71 / +

页数：13

共 62 条

[1] Phyto-oestrogens and Western diseases
Adlercreutz, H
Mazur, W
[J]. ANNALS OF MEDICINE, 1997, 29 (02) : 95 - 120
[2] AKIYAMA T, 1987, J BIOL CHEM, V262, P5592
[3] ALDERCREUTZ H, 1986, J STEROID BIOCHEM, V24, P289
[4] ALDERCREUTZ H, 1998, BAILLIERE CLIN ENDOC, V12, P605
[5] ALDERCREUTZ H, 1986, J STEROID BIOCHEM, V25, P791
[6] BARNES S, 1995, J CELL BIOCHEM, P181
[7] BARNES S, 1995, P SOC EXP BIOL MED, V208, P103
[8] Phyto-oestrogens: Where are we now?
Bingham, SA
Atkinson, C
Liggins, J
Bluck, L
Coward, A
[J]. BRITISH JOURNAL OF NUTRITION, 1998, 79 (05) : 393 - 406
[9] Bylund A, 2000, PROSTATE, V42, P304, DOI 10.1002/(SICI)1097-0045(20000301)42:4<304::AID-PROS8>3.0.CO
[10] 2-Z

← 1 2 3 4 5 6 7 →