Growth of human endothelial cells on plasma-treated polyethyleneterephthalate surfaces

被引：15

作者：

Mirenghi, L ^{[1
]}

Ramires, PA ^{[1
]}

Pentassuglia, RE ^{[1
]}

Rotolo, P ^{[1
]}

Romito, A ^{[1
]}

机构：

[1] Ctr Nazl Ric Sviluppo Mat PASTIS CNRSM, I-72100 Brindisi, Italy

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 2000年 / 11卷 / 05期

关键词：

D O I：

10.1023/A:1008929902205

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

Different methods have been proposed to reduce the surface thrombogenicity of small caliber vascular grafts, using plasma treatments of polymer surfaces in order to improve the adhesion and the proliferation of human endothelial cells (HEC). Plasma modified polyethyleneterephthalate (PET) substrates were employed to grow HEC, isolated from the umbilical vein. A combination of X-ray photoelectron spectroscopy (XPS) and Sessile contact angle (SCA) measurements allowed the study of the surface modifications produced soon after nitrogen and hydrogen plasma treatments with respect to an untreated PET substrate, used as reference. It was possible to select a number of PET substrates while actually performing the HEC seeding experiments. The HEC proliferation was evaluated by light microscope image analyzes. (C) 2000 Kluwer Academic Publishers.

引用

页码：327 / 331

页数：5

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