Synthesis and evaluation of a scintillant-containing solid support for use in combinatorial chemistry

被引：17

作者：

Clapham, B

Sutherland, AJ

机构：

[1] Aston Univ, Birmingham B4 7ET, W Midlands, England

[2] Nottingham Trent Univ, Dept Chem & Phys, Nottingham NG11 8NS, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 13期

关键词：

oxazoles; polymerisation; resins; combinatorial chemistry;

D O I：

10.1016/S0040-4039(00)00141-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A scintillant monomer, 2,5-diphenyl-4-vinyloxazole, has been synthesised and co-polymerised with 4-ethylstyrene, divinylbenzene and 4-vinylbenzyl chloride in the presence of a toluene porogen, to form a scintillant-containing macroporous resin. Despite prolonged exposure to organic solvent, this resin retains the ability to scintillate efficiently in the presence of ionising radiation. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2253 / 2256

页数：4

共 15 条

[11]

SUTHERLAND AJ, Patent No. 98216625

[12] SCINTILLATION PROXIMITY ASSAY - A SENSITIVE AND CONTINUOUS ISOTOPIC METHOD FOR MONITORING LIGAND RECEPTOR AND ANTIGEN-ANTIBODY INTERACTIONS [J].