Preimplantation genetic diagnosis

被引：12

作者：

Bick, David P.

Lau, Eduardo C.

机构：

[1] Med Coll Wisconsin, Dept Pediat, Div Med Genet, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Dept Obstet & Gynecol, Milwaukee, WI 53226 USA

[3] Med Coll Wisconsin, Human & Mol Genet Ctr, Milwaukee, WI 53226 USA

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 2006年 / 53卷 / 04期

关键词：

D O I：

10.1016/j.pcl.2006.05.006

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This article covers the rapidly advancing field of preimplantation genetic diagnosis (PGD), the molecular genetic analysis of cells taken from embryos formed through in vitro fertilization (IVF). The article focuses on current practices in patient management, relevant IVF and PGD procedures, molecular methods used in the genetic analysis, and technical difficulties that can affect test results. It discusses the growing list of indications for PGD including chromosomal disorders, monogenic disorders and human leukocyte antigen typing typing of embryos. The article also examines some of the emerging technologies being introduced into PGD.

引用

收藏

页码：559 / +

页数：20

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