A new entry to the preparation of pyrrolo[2,3-b]quinolines by an aza Wittig/electrocyclic ring-closure/nitrene insertion process.

被引：26

作者：

Molina, P

Alcantara, J

LopezLeonardo, C

机构：

[1] Depto. de Quimica Orgánica, Facultad de Química, Universidad de Murcia, E-30071, Murcia

来源：

TETRAHEDRON | 1997年 / 53卷 / 09期

关键词：

D O I：

10.1016/S0040-4020(97)00038-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the preparation of the pyrrolo[2,3-b]quinoline ring system involving the sequential formation of the pyridine ring (electrocyclic ring-closure) and the pyrrole (nitrene insertion reaction) rings. This approach is based on the regioselective formation of the iminophosphorane 2 from the bis(azide) 1, followed by aza Wittig reaction with isocyanates and further thermal treatment. (C) 1997 Elsevier Science Ltd.

引用

页码：3281 / 3286

页数：6

共 13 条

[1]

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[2] REACTIONS OF BETA-(LITHIOMETHYL)AZINES WITH NITRILES AS A ROUTE TO PYRROLOPYRIDINES, PYRROLOQUINOLINES, PYRROLOPYRAZINES, PYRROLOQUINOXALINES AND PYRROLOPYRIMIDINES [J].