Electrospinning of gelatin and gelatin/poly(L-lactide) blend and its characteristics for wound dressing

被引：210

作者：

Gu, Shu-Ying ^{[1
,2
]}

Wang, Zhi-Mei ^{[1
]}

Ren, Jie ^{[1
,2
]}

Zhang, Chun-Yan ^{[1
]}

机构：

[1] Tongji Univ, Sch Mat Sci & Engn, Inst Nano & Biopolymer Mat, Shanghai 200092, Peoples R China

[2] Tongji Univ, Sch Mat Sci & Engn, Minist Educ, Key Lab Adv Civil Engn Mat, Shanghai 200092, Peoples R China

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2009年 / 29卷 / 06期

关键词：

Biocompatibility; Electrospinning; Gelatin; Morphology; Wound dressing; ARTIFICIAL SKIN; NANOFIBERS; SCAFFOLD; CELL; FABRICATION; MEMBRANE; FIBERS; OPTIMIZATION; DESIGN; ACID);

D O I：

10.1016/j.msec.2009.02.010

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

082905 [生物质能源与材料]; 100103 [病原生物学];

摘要：

Gelatin nanofibres were electrospun from its aqueous acetic acid solution. Electrospinning parameters, such as concentration of aqueous acetic acid and gelatin solutions, electric field and spinning distance, were examined to investigate the electrospinnability of gelatin solutions and the morphology of gelatin nanofibrous mats. Nanofibrous mats from poly(L-lactide) (PLLA) and gelatin/PLLA solutions were obtained. The electrospun mats showed controlled evaporative water loss, promoted fluid drainage ability, and excellent biocompatibility, and therefore have a potential application as wound dressing. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：1822 / 1828

页数：7

共 42 条

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