Spectrophotometric measurement of antioxidant properties of flavones and flavonols against superoxide anion

被引:122
作者
Magnani, L
Gaydou, EM
Hubaud, JC
机构
[1] Fac Sci & Tech St Jerome, Lab Phytochim Marseille, F-13397 Marseille 20, France
[2] DIPTA, F-13855 Aix En Provence 3, France
关键词
flavones; hydroxylation; methoxylation; radical scavengers; superoxide anion; free radicals; anti- or pro-oxidant activity;
D O I
10.1016/S0003-2670(00)00717-0
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The antioxidant properties of 12 hydroxyflavones (including flavonols) and eight methoxyflavones were evaluated using the pyrogallol UV-VIS spectrophotometric method to generate superoxide anion. Pro- and antioxidant activity depends of the flavone concentration in the medium. Results show that the hydroxylation (on the C ring) of the 3- position (flavonols) enhanced antioxidant properties more than methoxylation. A similar phenomenon is observed for hydroxylation at the 2'-and 4'-positions (B ring). Hydroxylation or methoxylation on the 7- position (A ring), however, has a negative effect on the radical scavenger activity. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:209 / 216
页数:8
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