Facile synthesis of zwitterionic diblock copolymers without protecting group chemistry

被引：84

作者：

Bories-Azeau, X ^{[1
]}

Armes, SP ^{[1
]}

van den Haak, HJW ^{[1
]}

机构：

[1] Univ Sussex, Sch Life Sci, Dept Chem, Brighton BN1 9QJ, E Sussex, England

来源：

MACROMOLECULES | 2004年 / 37卷 / 07期

关键词：

D O I：

10.1021/ma035904u

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A versatile new route to zwitterionic diblock copolymers that avoids protecting group chemistry is reported. Various tertiary amine methacrylates are block copolymerized with 2-hydroxyethyl methacrylate to produce hydroxy-functional diblock precursors via sequential monomer addition. These low-polydispersity precursors are then treated with succinic anhydride under mild conditions to produce a range of new near-monodisperse zwitterionic diblock copolymers in which both blocks are weak polyelectrolytes. Thus, the final copolymers exhibit complex aqueous solution behavior (isoelectric points, schizophrenic micellization behavior, etc.) depending on the solution pH.

引用

页码：2348 / 2352

页数：5

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