Spectroscopy analysis of chitosan-glibenclamide hydrogels

被引：9

作者：

Delgadillo-Armendariz, Nancy-Liliana ^{[1
]}

Rangel-Vazquez, Norma-Aurea ^{[1
]}

Garcia-Castanon, Alejandra-Ibeth ^{[1
]}

机构：

[1] Inst Tecnol Aguascalientes, Div Estudios Posgrado & Invest, Aguascalientes, Mexico

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2014年 / 120卷

关键词：

Chitosan; Glibenclamide; FTIR; NMR; STRUCTURAL-ANALYSIS; QSAR; NANOPARTICLES;

D O I：

10.1016/j.saa.2013.09.112

中图分类号：

O433 [光谱学];

学科分类号：

070207 [光学];

摘要：

The structure of glibenclamide, 5-chloro-N-(2{4-[(cyclohexylamino)carbonyl] aminosulfonyl}phenyl) ethyl)-2-methoxybenzamide, an important antidiabetic drug, has been studied both chitosan using theoretical calculations like Gibbs free energy, electrostatic potential, FTIR and NMR spectroscopy. Fourier transform infrared (FT-IR) spectroscopy reveals information about the molecular interactions of chemical components and is useful to characterization of hydrogel. Nucleophilic and electrophilic regions were calculated using the electrostatic potential. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：524 / 528

页数：5

共 30 条

[1]

Antidiabetic activity of phenolic compounds from Pecan bark in streptozotocin-induced diabetic rats [J].

Abdallah, Hossam M. ;

Salama, Maha M. ;

Abd-Elrahman, Enas H. ;

El-Maraghy, Shohda A. .

PHYTOCHEMISTRY LETTERS, 2011, 4 (03) :337-341

[2]

Biodegradable chitosan nanogels crosslinked with genipin [J].

Arteche Pujana, Maite ;

Perez-Alvarez, Leyre ;

Cesteros Iturbe, Luis Carlos ;

Katime, Issa .

CARBOHYDRATE POLYMERS, 2013, 94 (02) :836-842

[3]

Rangel-Vázquez NA, 2010, J MEX CHEM SOC, V54, P192

[4]

Daphnia and fish toxicity of (benzo)triazoles: Validated QSAR models, and interspecies quantitative activity-activity modelling [J].

Cassani, Stefano ;

Kovarich, Simona ;

Papa, Ester ;

Roy, Partha Pratim ;

van der Wal, Leon ;

Gramatica, Paola .

JOURNAL OF HAZARDOUS MATERIALS, 2013, 258 :50-60

[5]

Florey K., 1981, ANAL PROFILES DRUG S, V10

[6]

Ganji F, 2009, IRAN POLYM J, V18, P63

[7]

Ultrafine hydrogel nanoparticles: Synthetic approach and therapeutic application in living cells [J].

Gao, De ;

Xu, Hao ;

Philbert, Martin A. ;

Kopelman, Raoul .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (13) :2224-2227

[8]

Glish L., 2001, J CHEM EDUC, V84, P2001

[9]

Vibrational analysis, electronic structure and nonlinear optical properties of Levofloxacin by density functional theory [J].

Gunasekaran, Sethu ;

Rajalakshmi, K. ;

Kumaresan, Subramanian .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2013, 112 :351-363

[10]

Osteogenic differentiation of mesenchymal stem cells in self-assembled peptide-amphiphile nanofibers [J].

Hosseinkhani, Hossein ;

Hosseinkhani, Mohsen ;

Tian, Furong ;

Kobayashi, Hisatoshi ;

Tabata, Yasuhiko .

BIOMATERIALS, 2006, 27 (22) :4079-4086

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