The Natural History of Primary Biliary Cirrhosis

被引:65
作者
Imam, Mohamad H. [1 ]
Lindor, Keith D. [2 ]
机构
[1] Univ N Dakota, Dept Internal Med, Fargo, ND USA
[2] Arizona State Univ, Coll Hlth Solut, Phoenix, AZ 85004 USA
关键词
primary biliary cirrhosis; ursodeoxycholic acid; liver transplantation; LIVER-TRANSPLANTATION; URSODEOXYCHOLIC ACID; ANTIMITOCHONDRIAL ANTIBODIES; RECURRENCE; EPIDEMIOLOGY; PATHOGENESIS; FEATURES; RISK;
D O I
10.1055/s-0034-1383731
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Our understanding of the natural history of primary biliary cirrhosis (PBC) has been evolving especially following the introduction of ursodeoxycholic acid (UDCA). A clearer understanding of disease pathophysiology and earlier diagnosis with increased prevalence of the disease worldwide has led to increased interest and improved outcomes in patients with PBC. In this article, the authors touch briefly on features of the disease and describe the natural history of PBC prior to and after the introduction of UDCA.
引用
收藏
页码:329 / 333
页数:5
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