In situ preparation of β-D-1-O-hydroxylamino carbohydrated polymers mediated by galactose oxidase

被引：23

作者：

Andreana, PR ^{[1
]}

Xie, WH ^{[1
]}

Cheng, HN ^{[1
]}

Qiao, L ^{[1
]}

Murphy, DJ ^{[1
]}

Gu, QM ^{[1
]}

Wang, PG ^{[1
]}

机构：

[1] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 11期

关键词：

D O I：

10.1021/ol0258379

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Galactose oxidase produced a C-6 aldehyde in various terminal-containing galactose hydroxylamines for the simultaneous in situ generation of an A-B type condensation for the construction of unique oxime polymers. Molecular weights of the corresponding polymers were determined to be in the range of 4200-8900 g/mol, respectively. This indicates that approximately 20-25 sugar units were incorporated in these unique polymers.

引用

收藏

页码：1863 / 1866

页数：4

相关论文

共 43 条

[21]

LEE YC, 1994, METHODS ENZYMOLOGY, V242

[22] Chemoselective ligation reactions with proteins, oligosaccharides and cells [J].

Lemieux, GA ;

Bertozzi, CR .

TRENDS IN BIOTECHNOLOGY, 1998, 16 (12) :506-513

[23] Enzymatic modification of hydroxyethylcellulose by transgalactosylation with β-galactosidases [J].

Li, J ;

Cheng, HN ;

Nickol, RG ;

Wang, PG .

CARBOHYDRATE RESEARCH, 1999, 316 (1-4) :133-137

[24] Polycaprolactone-modified hydroxyethylcellulose films prepared by lipase-catalyzed ring-opening polymerization [J].

Li, J ;

Xie, WH ;

Cheng, HN ;

Nickol, RG ;

Wang, PG .

MACROMOLECULES, 1999, 32 (08) :2789-2792

[25] Sugar-containing polyamines prepared using galactose oxidase coupled with chemical reduction [J].

Liu, XC ;

Dordick, JS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (02) :466-467

[26] A CHEMICAL APPROACH TO THE CONSTRUCTION OF MULTIMERIC PROTEIN ASSEMBLIES [J].

MUIR, TW .

STRUCTURE, 1995, 3 (07) :649-652

[27] Biorecognition of HPMA copolymer-adriamycin conjugates by lymphocytes mediated by synthetic receptor binding epitopes [J].

Omelyanenko, V ;

Kopecková, P ;

Prakash, RK ;

Ebert, CD ;

Kopecek, J .

PHARMACEUTICAL RESEARCH, 1999, 16 (07) :1010-1019

[28]

Ouchi Tatsuro, 1994, P465

[29] CHEMOENZYMATIC SYNTHESIS OF NOVEL SUCROSE-CONTAINING POLYMERS [J].

PATIL, DR ;

DORDICK, JS ;

RETHWISCH, DG .

MACROMOLECULES, 1991, 24 (11) :3462-3463

[30] ENZYMATIC-SYNTHESIS OF A SUCROSE-CONTAINING LINEAR POLYESTER IN NEARLY ANHYDROUS ORGANIC MEDIA [J].

PATIL, DR ;

RETHWISCH, DG ;

DORDICK, JS .

BIOTECHNOLOGY AND BIOENGINEERING, 1991, 37 (07) :639-646

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