Spontaneous remission of low-grade B-cell non-Hodgkin's lymphoma following withdrawal of methotrexate in a patient with rheumatoid arthritis: case report and review of the literature

被引:29
作者
Baird, RD [1 ]
van Zyl-Smit, RN
Dilke, T
Scott, SE
Rassam, SMB
机构
[1] Queen Marys Hosp, Dept Haematol, Sidcup DA14 6LR, Kent, England
[2] Queen Marys Hosp, Dept Rheumatol, Sidcup DA14 6LR, Kent, England
[3] Barnard Med Practice, Sidcup, Kent, England
关键词
lymphoma; methotrexate; toxicity; spontaneous regression; rheumatoid arthritis;
D O I
10.1046/j.1365-2141.2002.03619.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 69-year-old woman, who had suffered from deforming rheumatoid arthritis since the age of 40 years, had been treated with methotrexate for 3 years. She presented with a 7 week history of neck lymphadenopathy. Biopsy revealed low-grade marginal-zone B-cell non-Hodgkin's lymphoma. Computerized tomography and bone marrow biopsy confirmed stage IIIA disease. Spontaneous complete remission of the lymphoma was achieved 14 months after withdrawing immune suppression with methotrexate.
引用
收藏
页码:567 / 568
页数:2
相关论文
共 12 条
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