Innovation - Metabolite profiling: from diagnostics to systems biology

被引:576
作者
Fernie, AR
Trethewey, RN
Krotzky, AJ
Willmitzer, L
机构
[1] Max Planck Inst Mol Plant Physiol, Dept Mol Physiol, D-14476 Golm, Germany
[2] Metan GmbH & Co KGaA, D-10589 Berlin, Germany
[3] Metan Hlth GmbH, D-10589 Berlin, Germany
关键词
D O I
10.1038/nrm1451
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The concept of metabolite profiling has been around for several decades, but only recent technical innovations have allowed metabolite profiling to be carried out on a large scale-with respect to both the number of metabolites measured and the number of experiments carried out. As a result, the power of metabolite profiling as a technology platform for diagnostics, and the research areas of gene-function analysis and systems biology, is now beginning to be fully realized.
引用
收藏
页码:763 / 769
页数:7
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