Head and neck cancer among marijuana users: A meta-analysis of matched case-control studies

被引：23

作者：

de Carvalho, M. F. F. ^{[1
]}

Dourado, M. R. ^{[2
]}

Fernandes, I. B. ^{[3
]}

Araujo, C. T. P. ^{[4
]}

Mesquita, A. T. ^{[4
]}

Ramos-Jorge, M. L. ^{[4
]}

机构：

[1] Univ Fed Minas Gerais, Fac Hlth Sci, Grad Program Dent, BR-31270901 Belo Horizonte, MG, Brazil

[2] Univ Campinas Unicamp, Piracicaba Dent Sch, Grad Program Oral Pathol, BR-13414903 Piracicaba, SP, Brazil

[3] Fed Univ Jequitinhonha & Mucuri Valleys UFVJM, Fac Hlth Sci, Grad Program Dent, BR-39100000 Diamantina, MG, Brazil

[4] Fed Univ Jequitinhonha & Mucuri Valleys UFVJM, Fac Hlth Sci, Dept Dent, BR-39100000 Diamantina, MG, Brazil

来源：

ARCHIVES OF ORAL BIOLOGY | 2015年 / 60卷 / 12期

关键词：

Cannabis sativa; Head and neck cancer; Case-control; Meta-analysis; SQUAMOUS-CELL CARCINOMA; POOLED ANALYSIS; NEVER DRINKERS; RISK-FACTORS; ORAL-CANCER; SMOKING; TOBACCO; CANNABINOIDS;

D O I：

10.1016/j.archoralbio.2015.09.009

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Objectives: The scientific literature presents conflicting data on a possible causal relationship between marijuana users and the development of head and neck cancer. Design: This study performed a systematic review with meta-analysis. Articles were selected from various electronic databases using keywords obtained from the Medical Subject Headings (MeSH). After reading by three reviewers and scoring of methodological quality, six articles (totaling nine case control studies) were assessed with Comprehensive Meta-Analysis (R) software. The value of effect (odds ratio) was calculated, which represented the chance of developing head and neck cancer between individuals who had smoked marijuana in their lifetime in models controlled for age, gender, race, and tobacco consumption. Results: Approximately 12.6% of cases and 14.3% of controls were marijuana users. The meta-analysis found no association between exposure and disease (OR = 1.021; IC 95% = 0.912-1.14; p = 0.718). Conclusion: No association between lifetime marijuana use and the development of head and neck cancer was found. The different methods of collection/presentation of results in the selected articles prevented other analyzes from being conducted. Additional studies are needed to assess for long-term effects. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：1750 / 1755

页数：6

共 29 条

[21] Association of Marijuana Smoking with Oropharyngeal and Oral Tongue Cancers: Pooled Analysis from the INHANCE Consortium [J].

Marks, Morgan A. ;

Chaturvedi, Anil K. ;

Kelsey, Karl ;

Straif, Kurt ;

Berthiller, Julien ;

Schwartz, Stephen M. ;

Smith, Elaine ;

Wyss, Annah ;

Brennan, Paul ;

Olshan, Andrew F. ;

Wei, Qingyi ;

Sturgis, Erich M. ;

Zhang, Zuo-Feng ;

Morgenstern, Hal ;

Muscat, Joshua ;

Lazarus, Philip ;

McClean, Michael ;

Chen, Chu ;

Vaughan, Thomas L. ;

Wunsch-Filho, Victor ;

Curado, Maria Paula ;

Koifman, Sergio ;

Matos, Elena ;

Menezes, Ana ;

Daudt, Alexander W. ;

Fernandez, Leticia ;

Posner, Marshall ;

Boffetta, Paolo ;

Lee, Yuan-Chin Amy ;

Hashibe, Mia ;

D'Souza, Gypsyamber .

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2014, 23 (01) :160-171

[22]

Moher D, 2009, PLOS MED, V6, DOI [10.1136/bmj.i4086, 10.1136/bmj.b2700, 10.1371/journal.pmed.1000097, 10.1186/2046-4053-4-1, 10.1016/j.ijsu.2010.02.007, 10.1016/j.ijsu.2010.07.299, 10.1136/bmj.b2535]

[23] Marijuana use and risk of oral squamous cell carcinoma [J].