A new and efficient synthesis of 2-azatryptophans

被引：23

作者：

Crestey, Francois ^{[1
]}

Collot, Valerie ^{[1
]}

Stiebing, Silvia ^{[1
]}

Rault, Sylvain ^{[1
]}

机构：

[1] Univ Caen, UFR Sci Pharmaceut, UPRESEA 3915, CERMN, F-14032 Caen, France

来源：

TETRAHEDRON | 2006年 / 62卷 / 33期

关键词：

D O I：

10.1016/j.tet.2006.05.061

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes a new and simple synthesis of 2-azatryptophans in five steps from 2-ethylaniline. This methodology allows to obtain either the amino acid or the amino ester, according to the treatment and the reaction time, and its scaling up for multigram synthesis. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：7772 / 7775

页数：4

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