Phytome: a platform for plant comparative genomics

被引:26
作者
Hartmann, Stefanie
Lu, Dihui
Phillips, Jason
Vision, Todd J. [1 ]
机构
[1] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Sch Lib & Informat Sci, Chapel Hill, NC 27599 USA
关键词
D O I
10.1093/nar/gkj045
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Phytome is an online comparative genomics resource that can be applied to functional plant genomics, molecular breeding and evolutionary studies. It contains predicted protein sequences, protein family assignments, multiple sequence alignments, phylogenies and functional annotations for proteins from a large, phylogenetically diverse set of plant taxa. Phytome serves as a glue between disparate plant gene databases both by identifying the evolutionary relationships among orthologous and paralogous protein sequences from different species and by enabling cross-references between different versions of the same gene curated independently by different database groups. The web interface enables sophisticated queries on lineage-specific patterns of gene/protein family proliferation and loss. This rich dataset is serving as a platform for the unification of sequence-anchored comparative maps across taxonomic families of plants. The Phytome web interface can be accessed at the following URL:http://www.phytome.org. Batch homology searches and bulk downloads are available upon free registration.
引用
收藏
页码:D724 / D730
页数:7
相关论文
共 49 条
[41]   The bioperl toolkit:: Perl modules for the life sciences [J].
Stajich, JE ;
Block, D ;
Boulez, K ;
Brenner, SE ;
Chervitz, SA ;
Dagdigian, C ;
Fuellen, G ;
Gilbert, JGR ;
Korf, I ;
Lapp, H ;
Lehväslaiho, H ;
Matsalla, C ;
Mungall, CJ ;
Osborne, BI ;
Pocock, MR ;
Schattner, P ;
Senger, M ;
Stein, LD ;
Stupka, E ;
Wilkinson, MD ;
Birney, E .
GENOME RESEARCH, 2002, 12 (10) :1611-1618
[42]   RASCAL: rapid scanning and correction of multiple sequence alignments [J].
Thompson, JD ;
Thierry, JC ;
Poch, O .
BIOINFORMATICS, 2003, 19 (09) :1155-1161
[43]   Database resources of the National Center for Biotechnology Information [J].
Wheeler, David L. ;
Barrett, Tanya ;
Benson, Dennis A. ;
Bryant, Stephen H. ;
Canese, Kathi ;
Chetvernin, Vyacheslav ;
Church, Deanna M. ;
DiCuccio, Michael ;
Edgar, Ron ;
Federhen, Scott ;
Geer, Lewis Y. ;
Kapustin, Yuri ;
Khovayko, Oleg ;
Landsman, David ;
Lipman, David J. ;
Madden, Thomas L. ;
Maglott, Donna R. ;
Ostell, James ;
Miller, Vadim ;
Pruitt, Kim D. ;
Schuler, Gregory D. ;
Sequeira, Edwin ;
Sherry, Steven T. ;
Sirotkin, Karl ;
Souvorov, Alexandre ;
Starchenko, Grigory ;
Tatusov, Roman L. ;
Tatusova, Tatiana A. ;
Wagner, Lukas ;
Yaschenko, Eugene .
NUCLEIC ACIDS RESEARCH, 2007, 35 :D5-D12
[44]   NONGLOBULAR DOMAINS IN PROTEIN SEQUENCES - AUTOMATED SEGMENTATION USING COMPLEXITY-MEASURES [J].
WOOTTON, JC .
COMPUTERS & CHEMISTRY, 1994, 18 (03) :269-285
[45]   The iProClass integrated database for protein functional analysis [J].
Wu, CH ;
Huang, HZ ;
Nikolskaya, A ;
Hu, ZZ ;
Barker, WC .
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2004, 28 (01) :87-96
[46]   PIRSF: family classification system at the Protein Information Resource [J].
Wu, CH ;
Nikolskaya, A ;
Huang, HZ ;
Yeh, LSL ;
Natale, DA ;
Vinayaka, CR ;
Hu, ZZ ;
Mazumder, R ;
Kumar, S ;
Kourtesis, P ;
Ledley, RS ;
Suzek, BE ;
Arminski, L ;
Chen, YX ;
Zhang, J ;
Cardenas, JL ;
Chung, S ;
Castro-Alvear, J ;
Dinkov, G ;
Barker, WC .
NUCLEIC ACIDS RESEARCH, 2004, 32 :D112-D114
[47]   The Protein Information Resource [J].
Wu, CH ;
Yeh, LSL ;
Huang, HZ ;
Arminski, L ;
Castro-Alvear, J ;
Chen, YX ;
Hu, ZZ ;
Kourtesis, P ;
Ledley, RS ;
Suzek, BE ;
Vinayaka, CR ;
Zhang, J ;
Barker, WC .
NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :345-347
[48]   InterProScan - an integration platform for the signature-recognition methods in InterPro [J].
Zdobnov, EM ;
Apweiler, R .
BIOINFORMATICS, 2001, 17 (09) :847-848
[49]   ATV: display and manipulation of annotated phylogenetic trees [J].
Zmasek, CM ;
Eddy, SR .
BIOINFORMATICS, 2001, 17 (04) :383-384