A combinatorial library of photocrosslinkable and degradable materials

被引:123
作者
Anderson, Daniel G.
Tweedie, Catherine A.
Hossain, Naushad
Navarro, Sergio M.
Brey, Darren M.
Van Vliet, Krystyn J.
Langer, Robert
Burdick, Jason A.
机构
[1] MIT, Canc Res Ctr, Cambridge, MA 02139 USA
[2] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
[3] MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA
关键词
D O I
10.1002/adma.200600529
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A library of acrylate-terminated poly(beta-amino ester)s is synthesized in parallel (see figure and inside cover) via a condensation reaction that combines primary or secondary amines with diacrylates. This library of macromers is then photopolymerized to form networks with a wide range of degradation and mechanical properties. Because of the diversity in properties, these polymers could be developed and screened for numerous applications ranging from microdevices to biomaterials.
引用
收藏
页码:2614 / +
页数:6
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