Molecular cloning and expression analysis of MPPα-2, a novel mouse transcript detected in a differential screen of pituitary libraries

被引：3

作者：

Miyamoto, T ^{[1
]}

Fiorenza, MT ^{[1
]}

Zhao, YG ^{[1
]}

Hasuike, S ^{[1
]}

Westphal, H ^{[1
]}

机构：

[1] NICHHD, Lab Mammalian Genes & Dev, NIH, Bethesda, MD 20892 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2002年 / 1577卷 / 01期

关键词：

protein phosphatase; differential screening; Lhx3; pituitary;

D O I：

10.1016/S0167-4781(02)00293-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We identified a novel isoform transcript, MPPalpha-2, of the mouse Mg2+-dependent protein phosphatase (MPP) alpha gene. The amino acid sequence encoded by MPPalpha-2 differs from the previously known MPPalpha-1 sequence only at the carboxyl terminal region. Northern and in situ hybridization analysis revealed differential expression patterns of these two transcripts in the embryo and in the adult organism, suggesting an elaborate regulation of the MPPalpha gene. Published by Elsevier Science B.V.

引用

页码：109 / 112

页数：4

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