Optimized interleaved whole-brain 3D double inversion recovery (DIR) sequence for imaging the neocortex

被引:24
作者
Boulby, PA
Symms, MR
Barker, GJ
机构
[1] UCL, Dept Clin & Expt Epilepsy, Inst Neurol, London, England
[2] UCL, Dept Neuroinflammat, Inst Neurol, London, England
[3] Kings Coll London, Neuroimaging Res Grp, Inst Psychiat, London WC2R 2LS, England
关键词
double inversion recovery; gray matter; 3D; imaging; cortex;
D O I
10.1002/mrm.20088
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
For a substantial number of individuals with neurological disorders, a conventional MRI scan does not reveal any obvious etiology; however, it is believed that abnormalities in the neocortical gray matter (GM) underlie many of these disorders. Attempts to image the neocortex are hindered by its thin, convoluted structure, and the partial volume (PV) effect. Therefore, we developed a 3D version of the double inversion recovery (DIR) sequence that incorporates an optimized interleaved (OIL) strategy to improve efficiency and allow high-quality, high-resolution imaging of GM. (C) 2004 Wiley-Liss, Inc.
引用
收藏
页码:1181 / 1186
页数:6
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