Plasmodium vivax and P-falciparum: Biological interactions and the possibility of cross-species immunity

被引:107
作者
Maitland, K [1 ]
Williams, TN [1 ]
Newbold, CI [1 ]
机构
[1] JOHN RADCLIFFE HOSP,INST MOL MED,OXFORD OX3 9DS,ENGLAND
来源
PARASITOLOGY TODAY | 1997年 / 13卷 / 06期
基金
英国惠康基金;
关键词
D O I
10.1016/S0169-4758(97)01061-2
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The question of whether infection of humans with one species of malaria parasite alters the course of infection with another has been largely ignored because no such interaction was found during studies of induced malaria in patients with neurosyphilis. However, in animal model systems some degree of cross-species interaction is the rule rather than the exception. Furthermore, recent epidemiological observations in Vanuatu in the South Pacific have suggested a biological interaction between the dominant species, Plasmodium vivax, and P. falciparum. Kathryn Maitland, Tom Williams and Chris Newbold here speculate on the basis of these observations and other published findings that infection with P. vivax may result in the development of immunity sufficient to ameliorate the clinical course of subsequent infections with the potentially lethal parasite P. falciparum.
引用
收藏
页码:227 / 231
页数:5
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