Design and reactivity of organic functional groups - Preparation and nucleophilic displacement reactions of imidazole-1-sulfonates (imidazylates)

被引：35

作者：

Vatele, JM ^{[1
]}

Hanessian, S ^{[1
]}

机构：

[1] UNIV MONTREAL,DEPT CHEM,MONTREAL,PQ H3C 3J7,CANADA

来源：

TETRAHEDRON | 1996年 / 52卷 / 32期

关键词：

S(N)2 displacement; imidazole-1-sulfonate group;

D O I：

10.1016/0040-4020(96)00586-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Imidazole-1-sulfonate, a new type of leaving group by remote activation, allows facile S(N)2 substitution reactions at sterically crowded centers with various nucleophiles under mild conditions. It could be easily prepared from alcohols with cheap reagents in quantitative yield. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：10557 / 10568

页数：12

共 52 条

[21]

HAYASHI T, 1978, CHEM PHARM BULL, V26, P1786

[22] Concerning a d glucose 5 6-dichlorhydrin. [J].