Controlled stacking of 10 transition-metal ions inside a DNA duplex

被引：120

作者：

Clever, Guido H. ^{[1
]}

Carell, Thomas ^{[1
]}

机构：

[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 1-2期

关键词：

DNA structures; metal-base pairs; salen ligands; self-assembly; stacking interactions;

D O I：

10.1002/anie.200603099

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) A helical turn full of metal ions! The metal-salen base-pair concept allows the incorporation of up to 10 transition-metal ions into double strands of DNA (see picture; Mn gray spheres, C gray, N blue, P orange, O red). The crosslinking provided by the metal-salen complexes conveys a high stability to the self-assembled systems. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：250 / 253

页数：4

共 34 条

[1] Structure of a copper-mediated base pair in DNA [J].

Atwell, S ;

Meggers, E ;

Spraggon, G ;

Schultz, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (49) :12364-12367

[2]

BEROVA N, 2000, CIRCULAR DICHROISM, P713

[3] Transition metal Ligands as novel DNA-base substitutes [J].

Brotschi, C ;

Leumann, CJ .

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2003, 22 (5-8) :1195-1197

[4] SYNTHESIS FROM DNA OF A MOLECULE WITH THE CONNECTIVITY OF A CUBE [J].

CHEN, JH ;

SEEMAN, NC .

NATURE, 1991, 350 (6319) :631-633

[5] Building programmable jigsaw puzzles with RNA [J].

Chworos, A ;

Severcan, I ;

Koyfman, AY ;

Weinkam, P ;

Oroudjev, E ;

Hansma, HG ;

Jaeger, L .

SCIENCE, 2004, 306 (5704) :2068-2072

[6]

Clever G. H., 2005, ANGEW CHEM, V117, P7370

[7] A highly DNA-duplex-stabilizing metal-salen base pair [J].

Clever, GH ;

Polborn, K ;

Carell, T .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (44) :7204-7208

[8] Metal-salen-base-pair complexes inside DNA:: Complexation overrides sequence information [J].

Clever, Guido H. ;

Soeltl, Yvonne ;

Burks, Heather ;

Spahl, Werner ;

Carell, Thomas .

CHEMISTRY-A EUROPEAN JOURNAL, 2006, 12 (34) :8708-8718

[9]

DAVIDSON N, 1965, BIOCHEMISTRY-US, V4, P111

[10] DNA-programmed assembly of nanostructures [J].

Gothelf, KV ;

LaBean, TH .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2005, 3 (22) :4023-4037

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