Amygdala activation in the processing of neutral faces in social anxiety disorder:: Is neutral really neutral?

被引:188
作者
Cooney, Rebecca E. [1 ]
Atlas, Lauren Y. [1 ]
Joormann, Jutta [1 ]
Eugene, Fanny [1 ]
Gotlib, Ian H. [1 ]
机构
[1] Stanford Univ, Dept Psychol, Stanford, CA 94305 USA
关键词
amygdala; social phobia; social anxiety disorder; functional magnetic resonance imaging (fMRI);
D O I
10.1016/j.pscychresns.2006.05.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Previous research has suggested that Social Anxiety Disorder (SAD) is associated with a tendency to interpret ambiguous social stimuli in a threatening manner. The present study used event-related functional magnetic resonance imaging to examine patterns of neural activation in response to the processing of neutral facial expressions in individuals diagnosed with SAD and healthy controls (CTLs). The SAD participants exhibited a different pattern of amygdala activation in response to neutral faces than did the CTL participants, suggesting a neural basis for the biased processing of ambiguous social information in SAD individuals. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:55 / 59
页数:5
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