Effect of dietary dl-alpha-tocopherol on tissue alpha- and gamma-tocopherol and pulmonary hypertension syndrome (ascites) in broilers

被引:42
作者
Bottje, WG
Erf, GF
Bersi, TK
Wang, S
Barnes, D
Beers, KW
机构
[1] Department of Poultry Science, Ctr. of Excellence for Poultry Sci., University of Arkansas, Fayetteville
关键词
tocopherol; lung; liver; pulmonary hypertension syndrome; ascites;
D O I
10.1093/ps/76.11.1506
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
The objectives of this experiment were to determine the effects of high dietary levels of vitamin E on growth performance and pulmonary hypertension syndrome (PHS) mortality. Male broiler chicks (Cobb 500) were randomly assigned to one of four dietary treatments consisting of standard starter and grower diets supplemented with 0, 17, 46, and 87 mg dl-alpha-tocopherol acetate/kg. To encourage the development of PHS, air temperature in the house was 32 and 28 C for Weeks 1 and 2, dropped to 18 C during Week 3, and kept between 10 and 15 C during Weeks 4 through 7. Also, chicks were placed in floor pens on Litter used for five previous flocks and ventilation reduced to increase dust and ammonia in the house. Ammonia levels increased from an initial 18 to 36 ppm on Day 42 with the increase in ammonia corresponding to an obvious increase in dust in the air. Lung and Liver tissue obtained at 2, 5, and 7 wk of age were analyzed for tissue alpha- and gamma-tocopherol by liquid chromatography. Dietary vitamin E had no effect on body weight, feed intake, or feed efficiency. Cumulative PHS mortality through 7 wk of age was 21% and was also unaffected by dietary treatment. Liver and lung alpha-tocopherol concentrations exhibited a dose-response increase to dietary tocopherol and there was a high correlation between lung and liver tissue alpha-tocopherol (r = 0.72, P < 0.05). Whereas gamma-tocopherol concentrations in lung and liver were unaffected by dietary treatment, lister and lung exhibited age-dependent increases in both alpha- and gamma-tocopherol. Despite dose-dependent increases in tissue alpha-tocopherol, supplementation of diets with up to 87 mg dl-alpha-tocopherol acetate had no effect on growth performance or PHS mortality in broilers under the conditions used in this study.
引用
收藏
页码:1506 / 1512
页数:7
相关论文
共 33 条
[11]  
ERF GF, 1996, ARKANSAS NUTR C SEP, P113
[12]  
HALLIWELL B, 1990, METHOD ENZYMOL, V186, P1
[13]  
HOLLANDER D, 1981, J LAB CLIN MED, V97, P449
[14]  
HUCHZERMEYER FW, 1988, ONDERSTEPOORT J VET, V55, P5
[15]   PULMONARY-HYPERTENSION SYNDROME ASSOCIATED WITH ASCITES IN BROILERS [J].
HUCHZERMEYER, FW ;
DERUYCK, AMC .
VETERINARY RECORD, 1986, 119 (04) :94-94
[16]   UPTAKE, TRANSPORT AND DISTRIBUTION OF DL-ALPHA-TOCOPHERYL ACETATE COMPARED TO D-ALPHA-TOCOPHEROL IN RAINBOW-TROUT (SALMO-GAIRDNERI) [J].
HUNG, SSO ;
MOON, TW ;
HILTON, JW ;
SLINGER, SJ .
JOURNAL OF NUTRITION, 1982, 112 (08) :1590-1599
[17]   THE EFFECT OF VITAMIN-E ON PROSTAGLANDIN LEVELS IN THE IMMUNE ORGANS OF CHICKS DURING THE COURSE OF AN ESCHERICHIA-COLI INFECTION [J].
LAWRENCE, LM ;
MATHIAS, MM ;
NOCKELS, CF ;
TENGERDY, RP .
NUTRITION RESEARCH, 1985, 5 (05) :497-509
[18]  
Lopez-Coello C., 1986, IND AVICOLA, V33, P12
[19]  
MACHLIN LJ, 1991, HDB VITAMINS, P100
[20]   STUDIES ON AN ASCITIC SYNDROME IN YOUNG BROILERS .1. HEMATOLOGY AND PATHOLOGY [J].
MAXWELL, MH ;
ROBERTSON, GW ;
SPENCE, S .
AVIAN PATHOLOGY, 1986, 15 (03) :511-524