The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus

被引：27

作者：

Goldstein, F. ^{[1
]}

机构：

[1] St Joseph Hosp, F-75014 Paris, France

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2007年 / 59卷 / 01期

关键词：

borderline activity; staphylococci; antimicrobials;

D O I：

10.1093/jac/dkl429

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Low-level antibiotic resistance in Staphylococcus aureus is a frequently overlooked phenomenon, usually not detected by standard susceptibility testing procedures. It represents a gateway to high-level clinically relevant resistance. Moreover, low-level resistance may be associated with increased virulence, resistance to unrelated compounds and more successful in vivo survival.

引用

收藏

页码：1 / 4

页数：4

相关论文

共 37 条

[31] Increased expression of clumping factor and fibronectin-binding proteins by hemB mutants of Staphylococcus aureus expressing small colony variant phenotypes [J].

Vaudaux, P ;

Francois, P ;

Bisognano, C ;

Kelley, WL ;

Lew, DP ;

Schrenzel, J ;

Proctor, RA ;

McNamara, PJ ;

Peters, G ;

Von Eiff, C .

INFECTION AND IMMUNITY, 2002, 70 (10) :5428-5437

[32] In vivo emergence of subpopulations expressing teicoplanin or vancomycin resistance phenotypes in a glycopeptide-susceptible, methicillin-resistant strain of Staphylococcus aureus [J].

Vaudaux, P ;

Francois, P ;

Berger-Bächi, B ;

Lew, DP .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 47 (02) :163-170

[33]

von Eiff C, 2000, BERL MUNCH TIERARZTL, V113, P321

[34] Comparative in vitro activity of ceftobiprole against staphylococci displaying normal and small-colony variant phenotypes [J].

von Eiff, C ;

Friedrich, AW ;

Becker, K ;

Peters, G .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (10) :4372-4374

[35] Linezolid resistance in clinical isolates of Staphylococcus aureus [J].

Wilson, P ;

Andrews, JA ;

Charlesworth, R ;

Walesby, R ;

Singer, M ;

Farrell, DJ ;

Robbins, M .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 (01) :186-187

[36] Monitoring in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm infection model [J].

Yu, J ;

Wu, J ;

Francis, KP ;

Purchio, TF ;

Kadurugamuwa, JL .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 55 (04) :528-534

[37] Activities of the combination of quinupristin-dalfopristin with rifampin in vitro and in experimental endocarditis due to Staphylococcus aureus strains with various phenotypes of resistance to macrolide-lincosamide-streptogramin antibiotics [J].

Zarrouk, V ;

Bozdogan, B ;

Leclercq, R ;

Garry, L ;

Feger, C ;

Carbon, C ;

Fantin, B .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (04) :1244-1248

← 1 2 3 4 →