A solvent-free synthesis of coumarins via Pechmann condensation using heterogeneous catalyst

被引：92

作者：

Maheswara, Muchchintala ^{[1
]}

Siddaiah, Vidavalur ^{[1
]}

Damu, Guri Lakishmi Vasantha ^{[1
]}

Rao, Yeffa Koteswara ^{[1
]}

Rao, Chunduti Venkata ^{[1
]}

机构：

[1] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2006年 / 255卷 / 1-2期

关键词：

phenols; ethyl acetoacetate; methyl acetoacetate; cournarins; HClO4 center dot SiO2; recyclable heterogeneous catalyst; solvent-free conditions;

D O I：

10.1016/j.molcata.2006.03.051

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Substituted coumarins are synthesized from phenols and ethyl acetoacetate or methyl acetoacetate via Pechmann condensation using heterogeneous recyclable catalyst (HClO4 (.) SiO2) under solvent-free conditions. This method is simple, cost effective, requires short reaction times and benefits from the elimination of production of acidic waste streams generated with conventional acid catalyst to give good yields. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：49 / 52

页数：4

共 32 条

[11] SYNTHESIS OF 7-HYDROXYCOUMARINS CATALYZED BY SOLID ACID CATALYSTS [J].

HOEFNAGEL, AJ ;

GUNNEWEGH, EA ;

DOWNING, RS ;

VANBEKKUM, H .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (02) :225-226

[12] USE OF CATION EXCHANGE RESINS IN ORGANIC REACTIONS .1. VON PECHMANN REACTION [J].

JOHN, EV ;

ISRAELSTAM, SS .

JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (01) :240-&

[13]

Johnson J.R., 1942, Organic Reactions, Org. React., V1, P210, DOI DOI 10.1002/0471264180.OR001.08

[14]

Jones G., 1967, ORGANICREACTIONS, V15, P204, DOI [DOI 10.1002/0471264180.OR015.02, 10.1002/0471264180.or015.02]

[15] Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme [J].

Kayser, O ;

Kolodziej, H .

PLANTA MEDICA, 1997, 63 (06) :508-510

[16]

Kennedy RO, 1997, COUMARINS BIOL APPL

[17]

Khandekar AC, 2002, SYNLETT, P152

[18] Structure-activity relationships of some 3-substituted-4-hydroxycoumarins as HIV-1 protease inhibitors [J].

Kirkiacharian, S ;

Thuy, DT ;

Sicsic, S ;

Bakhchinian, R ;

Kurkjian, R ;

Tonnaire, T .

FARMACO, 2002, 57 (09) :703-708

[19]

Maeda M., 1984, Laser Dyes

[20]

Mitra AK, 1998, J INDIAN CHEM SOC, V75, P666

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