Heck Reactions with Palladium Nanoparticles in Ionic Liquids: Coupling of Aryl Chlorides with Deactivated Olefins

被引：110

作者：

Calo, Vincenzo ^{[1
]}

Nacci, Angelo ^{[1
]}

Monopoli, Antonio ^{[1
]}

Cotugno, Pietro ^{[1
]}

机构：

[1] Univ Bari, Dept Chem, CNR ICCOM, I-70126 Bari, Italy

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 33期

关键词：

aryl chlorides; colloids; Heck reaction; ionic liquids; palladium; CATALYST; CHLOROARENES; ACTIVATION; CHEMISTRY; ARYLATION; ALDEHYDES; BROMIDES; LIGANDS; SCOPE;

D O I：

10.1002/anie.200902337

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Smooth operators: Heck reactions of aryl chlorides were catalyzed by ligand-free palladium acetate in a molten mixture of tetraalkylammonium ionic liquids under aerobic and relatively mild conditions (see example). Deactivated electron-rich aryl chlorides reacted with a wide array of substituted alkenes under these conditions, which thus enabled the coupling of combinations of substrates that are commonly unreactive with traditional catalysts. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6101 / 6103

页数：3

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