Psoriatic arthritis

被引:252
作者
Gladman, Dafna D. [1 ]
机构
[1] Toronto Western Hosp, Ctr Prognosis Studies Rheumat Dis, Toronto, ON M5T 2S8, Canada
关键词
epidemiology; psoriatic arthritis; quality of life; treatment; QUALITY-OF-LIFE; PLACEBO-CONTROLLED TRIAL; PERIPHERAL JOINT DISEASE; TUMOR-NECROSIS-FACTOR; DOUBLE-BLIND; RHEUMATOID-ARTHRITIS; TNF-ALPHA; OSTEOCLAST DIFFERENTIATION; ANKYLOSING-SPONDYLITIS; METHOTREXATE THERAPY;
D O I
10.1111/j.1529-8019.2008.01215.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
Although there is still some controversy about the existence of psoriatic arthritis (PsA) as a specific form of inflammatory arthritis associated with psoriasis, epidemiological and clinical studies support the unique features of PsA. Because of lack of diagnostic or classification criteria, the disease has been thought of as uncommon. New classification criteria should facilitate case definition of PsA. Over the past several decades, it has become clear that the disease leads to serious disability and even increased mortality. Traditional medications have not been effective in preventing the progression of joint damage. New medications, including biologics, have emerged with potential to controlling the inflammation and arresting the progression of joint damage.
引用
收藏
页码:40 / 55
页数:16
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