A micro RNA-146a polymorphism is associated with coronary restenosis

被引：20

作者：

Hamann, L. ^{[1
]}

Glaeser, C. ^{[2
]}

Schulz, S. ^{[3
]}

Gross, M. ^{[4
]}

Franke, A. ^{[5
]}

Noethlings, U. ^{[6
]}

Schumann, R. R. ^{[1
]}

机构：

[1] Charite Univ Med Ctr, Inst Microbiol & Hyg, Berlin, Germany

[2] Univ Halle, Inst Human Genet & Med Biol, Halle, Germany

[3] Univ Halle Wittenberg, Univ Sch Dent Med, Dept Operat Dent & Periodontol, D-06108 Halle, Germany

[4] Charite Univ Med Ctr, Dept Cardiol, Berlin, Germany

[5] Univ Hosp Schleswig Holstein, Kiel, Germany

[6] Univ Kiel, Popgen Biobank, Inst Expt Med, Kiel, Germany

来源：

INTERNATIONAL JOURNAL OF IMMUNOGENETICS | 2014年 / 41卷 / 05期

关键词：

C-REACTIVE PROTEIN; STABLE ANGINA-PECTORIS; STENT IMPLANTATION; ARTERY-DISEASE; INFLAMMATION; RISK; INTERVENTION; ACTIVATION;

D O I：

10.1111/iji.12136

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学];

摘要：

The association of the miRNA-146a polymorphism rs2910164 with atherosclerosis and restenosis was investigated. We found no association with atherosclerosis; however, we found a negative association for the G/C (P=0.007) and a positive association for the C/C genotype with the risk of restenosis, which is the main drawback for cardiac surgery.

引用

页码：393 / 396

页数：4

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